BDBM50266762 CHEMBL218974

SMILES C[C@]1(COc2ccc(OC(F)(F)F)cc2)Cn2cc(nc2O1)[N+]([O-])=O

InChI Key InChIKey=GPWIINYCHXCGQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266762   

TargetCytochrome P450 3A4(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50266762(CHEMBL218974)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as decrease in formation of 6beta-hydroxytestosterone from testosterone after 10 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50266762(CHEMBL218974)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50266762(CHEMBL218974)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed