BDBM50266704 CHEMBL4083717

SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O

InChI Key InChIKey=GYPFKQQJLPOFKF-UHFFFAOYSA-N

Data  1 KI  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50266704   

TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataEC50:  0.510nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataEC50:  16nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataEC50:  8.80nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataIC50: 550nMAssay Description:Displacement of [125I]-NDP-MSH from mouse MC3R expressed in HEK293 cells after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-NDP-MSH from mouse MC4R expressed in HEK293 cells after 1 hr by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataKi:  15nMAssay Description:Antagonist activity at mouse MC4R expressed in HEK293 cells assessed as inhibition of NDP-MSH induced-cAMP accumulation after 2 hrs by alpha screen a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2020
Entry Details Article
PubMed