BDBM50266629 CHEMBL4061456

SMILES Cc1cncc(n1)-c1cn2c(ncc2cn1)-c1cccc(n1)N1CCCNCC1

InChI Key InChIKey=NIRPQZMBABINPZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266629   

TargetSerine/threonine-protein kinase pim-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50266629(CHEMBL4061456)
Affinity DataKi:  0.400nMAssay Description:Inhibition of PIM3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50266629(CHEMBL4061456)
Affinity DataKi:  0.5nMAssay Description:Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50266629(CHEMBL4061456)
Affinity DataKi:  16nMAssay Description:Inhibition of PIM2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2020
Entry Details Article
PubMed