BDBM50266628 CHEMBL4089586

SMILES Cc1cncc(n1)-c1cnc2cnn(-c3cccc(n3)N3CCCNCC3)c2c1

InChI Key InChIKey=PWDDNCBQYVPPFY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266628   

TargetSerine/threonine-protein kinase pim-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50266628(CHEMBL4089586)
Affinity DataKi:  0.400nMAssay Description:Inhibition of PIM3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50266628(CHEMBL4089586)
Affinity DataKi:  0.800nMAssay Description:Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50266628(CHEMBL4089586)
Affinity DataKi:  13nMAssay Description:Inhibition of PIM2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2020
Entry Details Article
PubMed