BDBM50266578 CHEMBL477650::N-{3-[2-(Dimethylamino)ethyl]-2-methyl-1H-inden-5-yl}-1-benzothiophene-3-sulfonamide

SMILES CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3csc4ccccc34)cc12

InChI Key InChIKey=XWXCMQFSARGQNK-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266578   

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266578(N-{3-[2-(Dimethylamino)ethyl]-2-methyl-1H-inden-5-...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as stimulation of cAMP level after 30 mins by HTRF assay Inhibition of ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266578(N-{3-[2-(Dimethylamino)ethyl]-2-methyl-1H-inden-5-...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266578(N-{3-[2-(Dimethylamino)ethyl]-2-methyl-1H-inden-5-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266578(N-{3-[2-(Dimethylamino)ethyl]-2-methyl-1H-inden-5-...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed