BDBM50266463 (Z/E)-(2S)-2-amino-6-([(5-bromo-2-oxo-indolin-3-ylidene)methyl]amino)hexanoic acid hydrochloride::CHEMBL458441

SMILES N[C@@H](CCCCN=CC1C(=O)Nc2ccc(Br)cc12)C(O)=O

InChI Key InChIKey=RAOMPTWVLNROTF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50266463   

TargetTyrosine-protein kinase ABL1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50266463((Z/E)-(2S)-2-amino-6-([(5-bromo-2-oxo-indolin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50266463((Z/E)-(2S)-2-amino-6-([(5-bromo-2-oxo-indolin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cMetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266463((Z/E)-(2S)-2-amino-6-([(5-bromo-2-oxo-indolin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50266463((Z/E)-(2S)-2-amino-6-([(5-bromo-2-oxo-indolin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50266463((Z/E)-(2S)-2-amino-6-([(5-bromo-2-oxo-indolin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50266463((Z/E)-(2S)-2-amino-6-([(5-bromo-2-oxo-indolin-3-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed