BDBM50266276 (2R)-3-(1-(4-isopropylphenyl)butylthio)-2-((S)-3-mercapto-2-methylpropanamido)propanoic acid::CHEMBL458450

SMILES CCCC(SC[C@H](NC(=O)[C@H](C)CS)C(O)=O)c1ccc(cc1)C(C)C

InChI Key InChIKey=OZVSYWQMNWTLKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266276   

TargetAngiotensin-converting enzyme(Human)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266276((2R)-3-(1-(4-isopropylphenyl)butylthio)-2-((S)-3-m...)
Affinity DataIC50: 420nMAssay Description:Inhibition of angiotensin-converting enzyme in whole blood by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Guinea pig)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266276((2R)-3-(1-(4-isopropylphenyl)butylthio)-2-((S)-3-m...)
Affinity DataIC50: 180nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed