BDBM50266169 5-(4-chlorobenzyl)-2-(naphthalen-1-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-imidazole::CHEMBL460167

SMILES Clc1ccc(Cc2cnc(-c3cccc4ccccc34)n2C2CCC3(CC2)OCCO3)cc1

InChI Key InChIKey=CBMWBVOLPFQNKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266169   

LigandPNGBDBM50266169(5-(4-chlorobenzyl)-2-(naphthalen-1-yl)-1-(1,4-diox...)
Affinity DataIC50: 877nMAssay Description:Antagonist activity at C5a receptor assessed as inhibition of C5a-induced elastase release in human neutrophils during degranulation preincubated 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266169(5-(4-chlorobenzyl)-2-(naphthalen-1-yl)-1-(1,4-diox...)
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]C5a from C5a receptor in cAMP differentiated human U937 cells by filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed