BDBM50266164 (S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide::CHEMBL468791

SMILES [O-][N+](=O)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1

InChI Key InChIKey=FKWJNVQXRLPCPN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266164   

TargetTranscriptional activator protein TraR(Agrobacterium tumefaciens)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50266164((S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Affinity DataIC50: 2.25E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscriptional activator protein LuxR(Vibrio fischeri (strain ATCC 700601 / ES114))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50266164((S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Affinity DataIC50: 960nMAssay Description:Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscriptional activator protein LuxR(Vibrio fischeri)
Larkin University

Curated by ChEMBL
LigandPNGBDBM50266164((S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at Aliivibrio fischeri ES114 LuxR after 4 to 8 hrs by luminescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed