BDBM50266101 (+/-)-N-(2-(4-chlorophenyl)-1-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl)-2-ethyl-N-(1,4-dioxaspiro[4.5]decan-8-yl)benzamide::CHEMBL513964

SMILES CCc1ccccc1C(=O)N(C(Cc1ccc(Cl)cc1)c1noc(C)n1)C1CCC2(CC1)OCCO2

InChI Key InChIKey=RXLFSZALAMVPJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266101   

LigandPNGBDBM50266101((+/-)-N-(2-(4-chlorophenyl)-1-(5-methyl-1,2,4-oxad...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at C5a receptor assessed as inhibition of C5a-induced elastase release in human neutrophils during degranulation preincubated 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266101((+/-)-N-(2-(4-chlorophenyl)-1-(5-methyl-1,2,4-oxad...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]C5a from C5a receptor in cAMP differentiated human U937 cells by filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed