BDBM50266092 CHEMBL468618::N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-6-(trifluoromethyl)-1H-benzo[d]imidazol-2-amine

SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nc3ccc(cc3[nH]2)C(F)(F)F)cc1C

InChI Key InChIKey=ATRPQMWXVVIWMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266092   

TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266092(N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266092(N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed