BDBM50265975 (S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2,5-dimethoxyphenyl)-4-oxobutanamide::CHEMBL467750

SMILES COc1ccc(OC)c(c1)C(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)C(N)=O

InChI Key InChIKey=LFVRPJOMCAYKBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265975   

TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50265975((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2,...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50265975((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2,...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human erythrocytes mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed