BDBM50265606 2-(4-chlorophenyl)-6-fluorobenzo[d]isothiazol-3(2H)-one::CHEMBL524449::TCMDC-124484

SMILES Fc1ccc2c(c1)sn(-c1ccc(Cl)cc1)c2=O

InChI Key InChIKey=CUZRZOGJMYSPPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265606   

TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50265606(2-(4-chlorophenyl)-6-fluorobenzo[d]isothiazol-3(2H...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50265606(2-(4-chlorophenyl)-6-fluorobenzo[d]isothiazol-3(2H...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant MIF tautomerase activity using 4-hydroxyphenylpyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed