BDBM50265353 4-(4'-methoxybiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridine::CHEMBL496752

SMILES COc1ccc(cc1)-c1ccc(Oc2cncc3sc(cc23)-c2nnn[nH]2)cc1

InChI Key InChIKey=OFLKEFYRFADJQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265353   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50265353(4-(4'-methoxybiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50265353(4-(4'-methoxybiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of MEK1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed