BDBM50265347 1-(3-fluoro-4-(4-(2-(isopropylthio)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)phenyl)ethanone::CHEMBL523397

SMILES CC(C)Sc1ccc(cc1C(=O)N1CCN(CC1)c1ccc(cc1F)C(C)=O)S(C)(=O)=O

InChI Key InChIKey=ZQJMACBNYQHHJD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265347   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265347(1-(3-fluoro-4-(4-(2-(isopropylthio)-5-(methylsulfo...)
Affinity DataEC50:  15nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265347(1-(3-fluoro-4-(4-(2-(isopropylthio)-5-(methylsulfo...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 2 expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed