BDBM50265346 1-(4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone::CHEMBL495510

SMILES CC(=O)c1ccc(N2CCN(CC2)C(=O)c2cc(ccc2OCC2CC2)S(C)(=O)=O)c(F)c1

InChI Key InChIKey=WBYYGBHFXXFGOM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265346   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265346(1-(4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)...)
Affinity DataEC50:  15nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265346(1-(4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 2 expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed