BDBM50265076 (R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2-yl)methoxy)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid::CHEMBL497772

SMILES COc1c(Br)ccc2oc(COc3ccc(cc3)-c3ccc(cc3)S(=O)(=O)N[C@H](C(C)C)C(O)=O)c(C)c12

InChI Key InChIKey=KQIFSUSWYMDFOC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50265076   

TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 42nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 81nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 135nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265076((R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed