BDBM50265044 (+/-)-2-amino-N-(2-(4-(4-chlorobenzylamino)piperidin-3-ylamino)-2-oxoethyl)-5-(trifluoromethyl)benzamide::CHEMBL497780

SMILES Nc1ccc(cc1C(=O)NCC(=O)NC1CNCCC1NCc1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=KFNLXORUUXKZHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265044   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265044((+/-)-2-amino-N-(2-(4-(4-chlorobenzylamino)piperid...)
Affinity DataIC50: 21.5nMAssay Description:Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50265044((+/-)-2-amino-N-(2-(4-(4-chlorobenzylamino)piperid...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed