BDBM50265037 (R)-N4-hydroxy-N1-((S)-1-((S)-2-methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-yl)-2-(3-(2-methylbiphenyl-4-yl)propyl)succinamide::CHEMBL503231

SMILES COC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(c(C)c1)-c1ccccc1)CC(=O)NO)C(C)(C)C)c1ccccc1

InChI Key InChIKey=NFPKLGKUZSGXBR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50265037   

TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265037((R)-N4-hydroxy-N1-((S)-1-((S)-2-methoxy-1-phenylet...)
Affinity DataIC50: 930nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265037((R)-N4-hydroxy-N1-((S)-1-((S)-2-methoxy-1-phenylet...)
Affinity DataIC50: 560nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265037((R)-N4-hydroxy-N1-((S)-1-((S)-2-methoxy-1-phenylet...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265037((R)-N4-hydroxy-N1-((S)-1-((S)-2-methoxy-1-phenylet...)
Affinity DataIC50: 750nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265037((R)-N4-hydroxy-N1-((S)-1-((S)-2-methoxy-1-phenylet...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed