BDBM50265015 CHEMBL497575::methyl 1-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazol-1-yl)phenoxy)propyl)piperidine-4-carboxylate

SMILES COC(=O)C1CCN(CCCOc2ccc(cc2)-n2c(nc3cc(F)ccc23)-c2ccccn2)CC1

InChI Key InChIKey=RMQURPVWFQWESL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265015   

TargetHistamine H3 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50265015(methyl 1-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50265015(methyl 1-(3-(4-(5-fluoro-2-(pyridin-2-yl)-1H-benzo...)
Affinity DataKi:  49nMAssay Description:Binding affinity to human ERG assessed as rubidium efflux at 5 ug/mL pre-equilibrated for 30 mins by DiBAC4(3)-based flame atomic absorbance spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed