BDBM50264841 CHEMBL4076767

SMILES COc1cc(ccc1Nc1nc(NC2CCCCC2)c2cc[nH]c2n1)N1CCOCC1

InChI Key InChIKey=YIGQSLKUNKHIBI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50264841   

TargetDual specificity protein kinase TTK(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50: 356nMAssay Description:Inhibition of recombinant human GST-tagged Mps1/TTK (507 to 1400 residues) using recombinant cetn2 as substrate in presence of [gamma-32P]ATP measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50: 891nMAssay Description:Inhibition of human FAK/PTK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of human JNK1 using ATF2 as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details Article
PubMed
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50264841(CHEMBL4076767)
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of human SYK using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details Article
PubMed