BDBM50264815 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5-dimethylisoxazol-4-yl)-N-hydroxypiperidine-4-carboxamide::CHEMBL484262

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)c1c(C)noc1C)C(=O)NO

InChI Key InChIKey=BBCCMNOZBPHYAJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50264815   

TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264815(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264815(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264815(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264815(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264815(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50: 664nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264815(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed