BDBM50264814 (2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3-dihydroxybutanamide::CHEMBL484261

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H]([C@H](C)O)C(=O)NO

InChI Key InChIKey=VMOSDDURWLNMNG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50264814   

TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 777nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 582nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 961nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 96nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 35nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264814((2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed