BDBM50264778 (E)-1-morpholino-3-(4-(2-(pyridin-3-ylmethoxy)phenylthio)-2,3-bis(trifluoromethyl)phenyl)prop-2-en-1-one::4-{(2E)-3-[4-{[2-(pyridin-3-ylmethoxy)phenyl]sulfanyl}-2,3-bis(trifluoromethyl)phenyl]prop-2-enoyl}morpholine::CHEMBL487705

SMILES c1ccc(c(c1)OCc2cccnc2)Sc3ccc(c(c3C(F)(F)F)C(F)(F)F)\C=C\C(=O)N4CCOCC4

InChI Key InChIKey=ZRIKDHLPCRURPX-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264778   

TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264778(4-{(2E)-3-[4-{[2-(pyridin-3-ylmethoxy)phenyl]sulfa...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)