BDBM50264773 4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-yloxy)-N,N-dimethylbiphenyl-4-carboxamide::CHEMBL489812

SMILES CN(C)C(=O)c1ccc(cc1)-c1ccc(Oc2cncc3sc(cc23)-c2nnn[nH]2)cc1

InChI Key InChIKey=FEEXBZJKUGASDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264773   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264773(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264773(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of MEK1 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed