BDBM50264726 1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one::CHEMBL483251

SMILES Clc1cc2nc([nH]c2cc1Cl)N1CCC2(CC1)OC(=O)c1ccccc21

InChI Key InChIKey=GHPUUPNFOOAKIE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50264726   

TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to NPY Y1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to NPY Y2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to NPY Y4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50264726(1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed