BDBM50264709 (R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamino)ethyl)phenoxy)-2-pivalamidobenzoic acid::CHEMBL491645

SMILES CC(C)(C)C(=O)Nc1ccc(Oc2cccc(CCNC[C@H](O)c3cccc(Cl)c3)c2)cc1C(O)=O

InChI Key InChIKey=KSUHGFRCLCFQDZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264709   

TargetBeta-3 adrenergic receptor(Dog)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264709((R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamin...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at dog cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264709((R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamin...)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264709((R)-5-(3-(2-(2-(3-chlorophenyl)-2-hydroxyethylamin...)
Affinity DataEC50:  620nMAssay Description:Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed