BDBM50264671 CHEMBL490215::rac-3-(4-isopropylphenyl)-N-(1-methoxypropan-2-yl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide

SMILES COCC(C)NC(=O)c1cnc2c(cnn2c1C)-c1ccc(cc1)C(C)C

InChI Key InChIKey=CGGPQQYOXKBDOB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264671   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264671(rac-3-(4-isopropylphenyl)-N-(1-methoxypropan-2-yl)...)
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50264671(rac-3-(4-isopropylphenyl)-N-(1-methoxypropan-2-yl)...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed