BDBM50264613 7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one::CHEMBL484678

SMILES O=C1NCc2cccc(-c3cc4cc(OCc5ccccc5)ccc4[nH]3)c12

InChI Key InChIKey=UIQCZMYFTSFLPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264613   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264613(7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one | ...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264613(7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one | ...)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264613(7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed