BDBM50264612 7-(1H-indol-2-yl)isoindolin-1-one::CHEMBL482621

SMILES O=C1NCc2cccc(-c3cc4ccccc4[nH]3)c12

InChI Key InChIKey=LEXHMAXLGJIDED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264612   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264612(7-(1H-indol-2-yl)isoindolin-1-one | CHEMBL482621)
Affinity DataIC50: 144nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264612(7-(1H-indol-2-yl)isoindolin-1-one | CHEMBL482621)
Affinity DataIC50: 100nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264612(7-(1H-indol-2-yl)isoindolin-1-one | CHEMBL482621)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed