BDBM50264580 7-(5-methoxy-1H-indol-2-yl)isoindolin-1-one::CHEMBL520975

SMILES COc1ccc2[nH]c(cc2c1)-c1cccc2CNC(=O)c12

InChI Key InChIKey=FUUBYTOMQKCISV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264580   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264580(7-(5-methoxy-1H-indol-2-yl)isoindolin-1-one | CHEM...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264580(7-(5-methoxy-1H-indol-2-yl)isoindolin-1-one | CHEM...)
Affinity DataIC50: 338nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50264580(7-(5-methoxy-1H-indol-2-yl)isoindolin-1-one | CHEM...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed