BDBM50264040 3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)sulfanyl]propanoic acid::CHEMBL492025

SMILES CC1=C(SCCC(O)=O)C(=O)c2ccccc2C1=O

InChI Key InChIKey=YQPMAEULEMJCMG-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50264040   

TargetM-phase inducer phosphatase 2(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of human recombinant fused MBP-CDC25B3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of CDC25A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of CDC25B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed