BDBM50264023 8-cyano-2-hydroxy-6,11-dihydro-5H-benzo[a]carbazole-3-carboxylic acid::CHEMBL521797

SMILES OC(=O)c1cc2CCc3c([nH]c4ccc(cc34)C#N)-c2cc1O

InChI Key InChIKey=UOGGLOWBPARNFY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264023   

TargetThrombopoietin receptor(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264023(8-cyano-2-hydroxy-6,11-dihydro-5H-benzo[a]carbazol...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human thrombopoietin receptor in Ba/F3 cells assessed as activation of Stat5 response element-driven reporter gene expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed