BDBM50264022 2-hydroxy-10-(trifluoromethyl)-6,11-dihydro-5H-benzo[a]carbazole-3-carboxylic acid::CHEMBL523147

SMILES OC(=O)c1cc2CCc3c([nH]c4c(cccc34)C(F)(F)F)-c2cc1O

InChI Key InChIKey=NSJAYSAFWGEXDS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264022   

TargetThrombopoietin receptor(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264022(2-hydroxy-10-(trifluoromethyl)-6,11-dihydro-5H-ben...)
Affinity DataEC50:  7.83E+3nMAssay Description:Agonist activity at human thrombopoietin receptor in Ba/F3 cells assessed as activation of Stat5 response element-driven reporter gene expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed