BDBM50264007 CHEMBL489182::N-(2,4-Disulfamoyl-5-trifluoromethyl-phenyl)-2-(7-methoxy-2-oxo-2H-chromen-4-yl)-acetamide::N-(2,4-disulfamoyl-5-(trifluoromethyl)phenyl)-2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamide

SMILES COc1ccc2c(CC(=O)Nc3cc(c(cc3S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F)cc(=O)oc2c1

InChI Key InChIKey=NFLMNEBPJVSVBV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50264007   

TargetCarbonic anhydrase 12(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50264007(N-(2,4-disulfamoyl-5-(trifluoromethyl)phenyl)-2-(7...)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50264007(N-(2,4-disulfamoyl-5-(trifluoromethyl)phenyl)-2-(7...)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 catalytic domain preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50264007(N-(2,4-disulfamoyl-5-(trifluoromethyl)phenyl)-2-(7...)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50264007(N-(2,4-disulfamoyl-5-(trifluoromethyl)phenyl)-2-(7...)
Affinity DataKi:  120nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed