BDBM50263939 2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoyl-phenyl)-acetamide::2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoylphenyl)acetamide::CHEMBL492022

SMILES COc1ccc2c(CC(=O)Nc3cccc(c3)S(N)(=O)=O)cc(=O)oc2c1

InChI Key InChIKey=OWQJSCXFFPCNIJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50263939   

TargetCarbonic anhydrase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263939(2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoyl...)
Affinity DataKi:  16nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263939(2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoyl...)
Affinity DataKi:  55nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263939(2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoyl...)
Affinity DataKi:  59nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 catalytic domain preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263939(2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-N-(3-sulfamoyl...)
Affinity DataKi:  94nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed