BDBM50263899 CHEMBL492030::N-methyl-N-[2-(piperidin-1-yl)ethyl]-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxamide

SMILES CN(CCN1CCCCC1)C(=O)N1CCC2(Cc3ccccc3C2)CC1

InChI Key InChIKey=RURNSGIUVDPHQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263899   

TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50263899(N-methyl-N-[2-(piperidin-1-yl)ethyl]-1,3-dihydrosp...)
Affinity DataIC50: 530nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of (R)-alpha-methylhistamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed