BDBM50263527 CHEMBL4087767

SMILES C[C@H]1[C@H](F)C[C@H](N1S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(ncn1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=KZYIBERUTGMWIW-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263527   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Pharmaron-Beijing

Curated by ChEMBL

LigandBDBM50263527(CHEMBL4087767)Copy SMILESCopy InChI

Affinity DataIC50: 64nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as inhibition of cinnamaldehyde-induced Ca2+ influx preincubated for 20 mins followed by...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/31/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetTransient receptor potential cation channel subfamily A member 1(Human)
Pharmaron-Beijing

Curated by ChEMBL

LigandBDBM50263527(CHEMBL4087767)Copy SMILESCopy InChI

Affinity DataIC50: 64nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Genentech

Curated by ChEMBL

LigandBDBM50263527(CHEMBL4087767)Copy SMILESCopy InChI

Affinity DataIC50: 390nMAssay Description:Antagonist activity at rat TRPA1More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL