BDBM50263519 CHEMBL4092287

SMILES C[C@H]1[C@H](F)C[C@H](N1S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(ncc1F)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=HGDUOYYDKBPRCV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263519   

LigandPNGBDBM50263519(CHEMBL4092287)
Affinity DataIC50: 8nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as inhibition of cinnamaldehyde-induced Ca2+ influx preincubated for 20 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50263519(CHEMBL4092287)
Affinity DataIC50: 36nMAssay Description:Inhibition of rat TRPA1 expressed in HEK293 cells assessed as inhibition of cinnamaldehyde-induced Ca2+ influx preincubated for 20 mins followed by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50263519(CHEMBL4092287)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRPM8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50263519(CHEMBL4092287)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50263519(CHEMBL4092287)
Affinity DataIC50: 8.40nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50263519(CHEMBL4092287)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at rat TRPA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed