BDBM50263512 4-(6,8-dioxaspiro[3.5]nonan-7-ylmethylamino)-2-cyano-N-methyl-6-((1-methylpiperidin-4-yl)methoxy)pyrimidine-5-carboxamide::CHEMBL477625

SMILES CNC(=O)c1c(NCC2OCC3(CCC3)CO2)nc(nc1OCC1CCN(C)CC1)C#N

InChI Key InChIKey=OMKHPTMZDIWOCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263512   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50263512(4-(6,8-dioxaspiro[3.5]nonan-7-ylmethylamino)-2-cya...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50263512(4-(6,8-dioxaspiro[3.5]nonan-7-ylmethylamino)-2-cya...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed