BDBM50263496 CHEMBL4091058

SMILES O=C1CCc2ccccc2N1CCCN1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=RYRTVXCXZPFWGO-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50263496   

TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  1.48E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  2.63E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  2.63E+3nMAssay Description:Agonist activity at human SP/Myc epitope-tagged muscarinic M4 receptor expressed in HEK293T cells assessed as RLuc8-fused Galphaq activation after 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  4.79E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  6.03E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50263496(CHEMBL4091058)
Affinity DataKi:  6.76E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed