BDBM50263419 4-(2-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)hydrazinyl)benzenesulfonamide::4-{N'-[2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetyl]-hydrazino}-benzenesulfonamide::CHEMBL478669

SMILES COc1ccc2c(CC(=O)NNc3ccc(cc3)S(N)(=O)=O)cc(=O)oc2c1

InChI Key InChIKey=NQHHVWHZFBPDRH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50263419   

TargetCarbonic anhydrase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263419(4-{N'-[2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetyl]...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263419(4-{N'-[2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetyl]...)
Affinity DataKi:  78nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263419(4-{N'-[2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetyl]...)
Affinity DataKi:  91nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263419(4-{N'-[2-(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetyl]...)
Affinity DataKi:  91nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 catalytic domain preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed