BDBM50263400 CHEMBL514198::N-(2-(bis(4-methoxyphenyl)methylamino)-2-oxoethyl)-4-fluorobenzamide

SMILES COc1ccc(cc1)C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccc(OC)cc1

InChI Key InChIKey=AGQQFHRGGSZZEV-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263400   

TargetSodium- and chloride-dependent glycine transporter 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263400(N-(2-(bis(4-methoxyphenyl)methylamino)-2-oxoethyl)...)
Affinity DataEC50:  2.31E+4nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 2 transfected in Flp-inTM-CHOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263400(N-(2-(bis(4-methoxyphenyl)methylamino)-2-oxoethyl)...)
Affinity DataEC50:  6.63E+3nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 transfected in Flp-inTM-CHOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263400(N-(2-(bis(4-methoxyphenyl)methylamino)-2-oxoethyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263400(N-(2-(bis(4-methoxyphenyl)methylamino)-2-oxoethyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263400(N-(2-(bis(4-methoxyphenyl)methylamino)-2-oxoethyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed