BDBM50263320 CHEMBL4074563

SMILES [O-][N+](=O)c1ccc(Nc2nc(nc3ncccc23)-c2ccccc2)cc1

InChI Key InChIKey=GCKSHISDHZSEHC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263320   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50263320(CHEMBL4074563)Copy SMILESCopy InChI

Affinity DataEC50:  5nMAssay Description:Activation of recombinant human ABCG2 ATPase activity expressed in baculovirus infected High five insect cell membranes after 20 mins by ascorbic aci...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/29/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50263320(CHEMBL4074563)Copy SMILESCopy InChI

Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as increase in accumulation of Hoechst 33342 preincubated for 30 mins followed by Hoechst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/29/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL