BDBM50263272 CHEMBL4077346

SMILES COc1ccc(Nc2nc(nc3ncccc23)-c2ccccc2)cc1

InChI Key InChIKey=NNIBESKDQBFDGM-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263272   

LigandPNGBDBM50263272(CHEMBL4077346)
Affinity DataEC50:  29nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as potentiation of irinotecan-induced decrease in cell viability after 72 hrs by MTT assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2020
Entry Details Article
PubMed
LigandPNGBDBM50263272(CHEMBL4077346)
Affinity DataEC50:  16nMAssay Description:Activation of recombinant human ABCG2 ATPase activity expressed in baculovirus infected High five insect cell membranes after 20 mins by ascorbic aci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2020
Entry Details Article
PubMed
LigandPNGBDBM50263272(CHEMBL4077346)
Affinity DataIC50: 238nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as increase in accumulation of Hoechst 33342 preincubated for 30 mins followed by Hoechst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2020
Entry Details Article
PubMed