BDBM50263163 CHEMBL4099814

SMILES Cc1cc(Nc2cc(nc(Nc3ccc(NC(=O)C4CCCCC4)cc3)n2)N2CCOCC2)n[nH]1

InChI Key InChIKey=RILVHGSNHHCBQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263163   

TargetReceptor-interacting serine/threonine-protein kinase 1(Mouse)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263163(CHEMBL4099814)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mouse)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263163(CHEMBL4099814)
Affinity DataIC50: 640nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed