BDBM50263079 CHEMBL4089624

SMILES Cc1cc(Nc2cc(nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)N2CCCCC2)n[nH]1

InChI Key InChIKey=MGJKOJVDJSINTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263079   

TargetReceptor-interacting serine/threonine-protein kinase 1(Mouse)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263079(CHEMBL4089624)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mouse)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263079(CHEMBL4089624)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed