BDBM50263043 CHEMBL501385::L-Isofagomine

SMILES OC[C@@H]1CNC[C@H](O)[C@H]1O

InChI Key InChIKey=QPYJXFZUIJOGNX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263043   

TargetLactase/phlorizin hydrolase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(L-Isofagomine | CHEMBL501385)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(L-Isofagomine | CHEMBL501385)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Bovine)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(L-Isofagomine | CHEMBL501385)
Affinity DataIC50: 6.11E+5nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(L-Isofagomine | CHEMBL501385)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(L-Isofagomine | CHEMBL501385)
Affinity DataIC50: 8.21E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(L-Isofagomine | CHEMBL501385)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human lysosomal beta-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed