BDBM50263040 5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyphenylamino)-1,2,4-triazolo[4,3-c]pyrimidine-8-carboxamide::CHEMBL476741

SMILES COc1cc(Nc2nc(NCC(C)(C)N)n3cnnc3c2C(N)=O)cc(OC)c1

InChI Key InChIKey=ICLJPAGXKRSDCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263040   

TargetTyrosine-protein kinase ZAP-70(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263040(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysine--tRNA ligase(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263040(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed