BDBM50262883 8-Methoxy-2-methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone trifluoroacetate::CHEMBL477152

SMILES COc1cccc2c1nc(C)n(-c1ccc(OCCCN3CCCC3)cc1)c2=O

InChI Key InChIKey=PIVGGMBOWQDOKF-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262883   

TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262883(8-Methoxy-2-methyl-3-(4-{[3-(1-pyrrolidinyl)propyl...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262883(8-Methoxy-2-methyl-3-(4-{[3-(1-pyrrolidinyl)propyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [35S]N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262883(8-Methoxy-2-methyl-3-(4-{[3-(1-pyrrolidinyl)propyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262883(8-Methoxy-2-methyl-3-(4-{[3-(1-pyrrolidinyl)propyl...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed